MyBioSource.com's PPARGC1A Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The PPARGC1A Antibody was generated using PGC1, PGC1 alpha, PGC1A, and PPARGC1A as the antigen and it reacts with Human, Mouse, and Rat.
Description
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination